Download e-book for iPad: Acute Coronary Syndromes in Clinical Practice by Deepak L. Bhatt, Anthony A Bavry

By Deepak L. Bhatt, Anthony A Bavry

ISBN-10: 1848003579

ISBN-13: 9781848003576

ISBN-10: 1848003587

ISBN-13: 9781848003583

Acute coronary syndromes (ACS) is an umbrella time period used to explain a sequence of symptoms indicative of myocardial ischemia, comprising risky angina, non-ST section elevation myocardial infarction, and ST section elevation myocardial infarction.

Managing Acute Coronary Syndromes in medical perform is an important source for the clinician within the administration of ACS. as well as supplying a accomplished evaluate of the epidemiology and scientific presentation of ACS, it additionally courses the reader via possibility review, threat stratification, prognosis, and remedy of ACS. The publication concludes with a dialogue on rising applied sciences within the therapy of ACS. The instruction manual layout and abundant use of illustrations make this pocketbook a very good source for common Practitioners, Emergency drugs Physicians, Nurses, Nurse Practitioners, Pharmacists, health practitioner Trainees, clinical scholars, Nursing scholars, and Paramedics who desire to maintain updated with fresh advances within the figuring out and therapy of ACS.

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Example text

The TIMI risk score is also useful in predicting which ACS patients will have a more favorable response to early invasive therapy when compared to medical management. The TACTICS (Treat Angina with Aggrastat and Determine the Cost of Therapy with an Invasive or Conservative Strategy)-TIMI 18 trial identified patients with an intermediate or high TIMI risk score who benefited from early invasive therapy, although the lowest risk patients appeared to do equally well on either approach [4]. The TIMI risk score incorporates seven variables (1 point for each variable) that independently predict a composite of death, myocardial infarction, or urgent revascularization at 14 days.

Lancet 1996; 348:1329–1339. 8. Hirsh J, Bhatt DL. Comparative benefits of clopidogrel and aspirin in high-risk patient populations lessons from the CAPRIE and CURE Studies. Arch Intern Med 2004; 164:2106–2110. 9. Yusuf S, Zhao F, Mehta SR, et al. Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation. N Engl J Med 2001; 345:494–502. 10. ; Clopidogrel in Unstable angina to prevent Recurrent Events trial (CURE) Investigators. Effects of pretreatment with clopidogrel and aspirin followed by long-term therapy in patients undergoing percutaneous coronary intervention: the PCI-CURE study.

21. Bhatt DL. Intensifying platelet inhibition – navigating between Scylla and Charybdis. N Engl J Med 2007; 357:2078–2081. 22. Chew DP, Bhatt DL, Sapp S, et al. Increased mortality with oral platelet glycoprotein IIb/ IIIa antagonists: a meta-analysis of phase III multicenter randomized trials. Circulation 2001; 103:201–206. 23. Quinn MJ, Plow EF, Topol EJ. Platelet glycoprotein IIb/IIIa inhibitors: recognition of a twoedged sword? Circulation 2002; 106:379–385. 24. Bhatt DL, Topol EJ. Current role of platelet glycoprotein IIb/IIIa inhibitors in acute coronary syndromes.

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Acute Coronary Syndromes in Clinical Practice by Deepak L. Bhatt, Anthony A Bavry

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